Effect of islet-activating protein (IAP) on α-adreno-ceptors-mediated contractile responses of rat vas deferens
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Effects of Mondia whitei extracts on the contractile responses of isolated rat vas deferens to potassium chloride and adrenaline
Objective: To investigate the effects of the methylene chloride:methanol (CH 2 Cl 2 :MeOH, Animal Physiology and 1:1) extract of the dried roots of Mondia whitei Linn and its hexane and methanol fractions on Phytopharmacology potassium chloride (KCl) and adrenaline (Adr)-induced contractions of rat vas deferens. Laboratory, Faculty of Science, Materials and Methods: Isolated strips of normal ad...
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15 صفحه اولThe sympathomimetic activity of fenfluramine hydrochloride on rat vas deferens.
1. The peripheral, pharmacological effects of the anorexigenic agent, fenfluramine hydrochloride, have been investigated on rat isolated vas deferens. 2. Characteristic spiked contractions were observed within 2 to 3 min after exposure to fenfluramine; these contractions reached a rate of around 13 per min and were of variable height. 3. Pre-treatment of vasa with the indirectly acting sympatho...
متن کاملEffects of bis(2-chloroethyl)sulfide on ATP receptor-mediated responses of the rat vas deferens: possible relationship to cytotoxicity.
Extracellular ATP is a broad-spectrum cytotoxic agent that produces effects via cell surface P2 purinoceptors. The ligand-gated P2X purinoceptor subtype has very high sequence homology with the RP-2 gene, which encodes for apoptosis. The P2X RNA found in rat vas deferens is expressed preferentially by apoptotic thymocytes. P2X purinoceptor-mediated phasic (twitch) motor responses of the isolate...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1983
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)60483-x